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Domino Reactions of Pyrazol-5-amines with Arylglyoxals and Malononitrile

Journal

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 52, Issue 8, Pages 1168-1172

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1070428016080121

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Domino reactions of 3-methylpyrazol-5-amine and 1-phenyl-3-methylpyrazol-5-amine with arylglyoxal hydrates and malononitrile in alcohol proceed regioselectively and lead to the formation of 6-aminopyrazolo[3,4-b]pyridine-5-carbonitrile.

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