4.1 Article

Synthesis and biological activity of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine

Journal

RUSSIAN CHEMICAL BULLETIN
Volume 65, Issue 2, Pages 537-545

Publisher

SPRINGER
DOI: 10.1007/s11172-016-1334-y

Keywords

3-hydroxypyridine; 4-deoxypyridoxine; phosphonium salts; antibacterial activity; antitumor activity

Funding

  1. Kazan Federal University for the Project part of the State Assignment in the Sphere of Scientific Activities
  2. Russian Foundation for Basic Research [14-03-31064]

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Methods for the synthesis of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine were developed. Some of obtained compounds possess high antibacterial and antitumor activity in vitro.

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