Journal
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL
Volume 49, Issue 4, Pages 512-514Publisher
SOC BRASILEIRA MEDICINA TROPICAL
DOI: 10.1590/0037-8682-0046-2016
Keywords
Toxoplasma gondii; Acute infection; High-risk pregnancy
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Funding
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2012/07716-9, 2013/15879-8, 2014/01706-7, 2014/09496-1]
- Brazilian Ministry of Science, Technology and Innovation - Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (PIBIC-CNPq) [135144/2014-0, 135229/2014-6]
- Brazilian Ministry of Science, Technology and Innovation - Fundacao de Apoio a Pesquisa e Extensao de Sao Jose do Rio Preto (FAPERP) [175/2015, 129/2015]
- Bolsa Auxilio a Pesquisa (BAP-FAMERP)
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Introduction: Toxoplasmosis during pregnancy can be severe; thus, it is essential to diagnose the disease via serological tests. Methods: An enzyme-linked immunosorbent assay (ELISA) was used to investigate anti-Toxoplasma gondii immunoglobulin A (IgA), M (IgM) and G (IgG) antibodies in 62 high-risk pregnant women. Results: Forty-three (69.4%) women were positive for IgA, 31 (50%) for IgG, and 57 (91.9%) for IgM; 4 (6,5%) were positive for IgA but negative for IgM; 10 (16.1%) were negative for IgA and IgM but positive for IgG. Conclusions: Testing for these antibodies can help diagnose infection in pregnant women, thereby contributing to clinical management.
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