Journal
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
Volume 14, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s12958-016-0173-x
Keywords
PCOS; Genetic; Insulin-resistance; Hyperandrogenism; Infertility; Metformin; Oral contraceptives; Myo-inositol
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Polycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5-10 % of women of reproductive age. It generally manifests with oligo/anovulatory cycles, hirsutism and polycystic ovaries, together with a considerable prevalence of insulin resistance. Although the aetiology of the syndrome is not completely understood yet, PCOS is considered a multifactorial disorder with various genetic, endocrine and environmental abnormalities. Moreover, PCOS patients have a higher risk of metabolic and cardiovascular diseases and their related morbidity, if compared to the general population.
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