Journal
REGULATORY TOXICOLOGY AND PHARMACOLOGY
Volume 75, Issue -, Pages 27-34Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yrtph.2015.12.016
Keywords
Cigarette mainstream smoke; Nicotine; Enzymatic hydrolysis; Tobacco alkaloids; Partial least squares regression (PLSR); Risk; Sensory attributes; Glucose
Categories
Ask authors/readers for more resources
Based on encouraged development of potential reduced-exposure products (PREPs) by the US Institute of Medicine, casings (glucose and peptides) added treatments (CAT) and enzymatic (protease and xylanase) hydrolysis treatments (EHT) were developed to study their effect on alkaloids reduction in tobacco and cigarette mainstream smoke (MS) and further investigate the correlation between sensory attributes and alkaloids. Results showed that the developed treatments reduced nicotine by 14.5% and 24.4% in tobacco and cigarette MS, respectively, indicating that both CAT and EHT are potentially effective for developing lower-risk cigarettes. Sensory and electronic nose analysis confirmed the significant influence of treatments on sensory and cigarette MS components. PLSR analysis demonstrated that tobacco alkaloids were positively correlated to the off-taste, irritation and impact attributes, and negatively correlated to the aroma and softness attributes. Additionally, nicotine and anabasine from tobacco leaves positively contributed to the impact attribute, while they negatively contributed to the aroma attribute (P < 0.05). Meanwhile, most alkaloids in cigarette MS positively contributed to the impact and irritation attributes (P < 0.05). Hence, this study paved a way to better understand the correlation between tobacco alkaloids and sensory attributes. (C) 2015 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available