Journal
REGENERATIVE MEDICINE
Volume 11, Issue 5, Pages 459-463Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/rme-2016-0031
Keywords
plastic surgery; platelet gel; platelet-rich plasma; radiodermatitis
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Aim: Bone osteoradionecrosis is a serious complication of radiation treatment. Current treatment approaches are not curative and treatment response is often poor leading to high social and healthcare costs. Case report: We report on the first case of osteoradionecrosis with successful restitutio ab integro by repeated administration of platelet gel (PLT-gel) and surgery in a critically ill patient. The administration of PLT-gel during a severe septic episode helped regeneration of bone and soft tissues, shortening the hospital stay of the patient. It was also noted that following applications of PLT-gel, both the use of morphine and the numbers of infective episodes were reduced. Conclusion: Additional studies are needed to confirm the promising effect of PLT-gel for the treatment of osteoradionecrosis.
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