Related references
Note: Only part of the references are listed.Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses
Nuno J. Machado et al.
MOLECULAR NEUROBIOLOGY (2017)
The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias
Ajith A. Welihinda et al.
CELLULAR SIGNALLING (2016)
Novel approaches for the management of depressive disorders
Manuella P. Kaster et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Agmatine produces antidepressant-like effects by activating AMPA receptors and mTOR signaling
Vivian Binder Neis et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2016)
Oral Inosine Persistently Elevates Plasma antioxidant capacity in Parkinson's disease
Shamik Bhattacharyya et al.
MOVEMENT DISORDERS (2016)
NMDAR inhibition-independent antidepressant actions of ketamine metabolites
Panos Zanos et al.
NATURE (2016)
Purine metabolism is dysregulated in patients with major depressive disorder
Toni Ali-Sisto et al.
PSYCHONEUROENDOCRINOLOGY (2016)
Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder
G. I. Papakostas et al.
MOLECULAR PSYCHIATRY (2015)
Region-specific alterations of AMPA receptor phosphorylation and signaling pathways in the pilocarpine model of epilepsy
Mark William Lopes et al.
NEUROCHEMISTRY INTERNATIONAL (2015)
Developmental exposure to manganese induces lasting motor and cognitive impairment in rats
Tanara V. Peres et al.
NEUROTOXICOLOGY (2015)
Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice
Vivian Binder Neis et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2015)
Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress
Manuella P. Kaster et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Antidepressant-like effect of zinc is dependent on signaling pathways implicated in BDNF modulation
Luana M. Manosso et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2015)
Purinergic system dysfunction in mood disorders: a key target for developing improved therapeutics
Robin Ortiz et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2015)
Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A1 and A2A receptor activation
Mauricio P. Cunha et al.
PURINERGIC SIGNALLING (2015)
Adenosine A1 Receptor-Dependent Antinociception Induced by Inosine in Mice: Pharmacological, Genetic and Biochemical Aspects
Francisney Pinto Nascimento et al.
MOLECULAR NEUROBIOLOGY (2015)
Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress
Dexiang Liu et al.
BEHAVIOURAL BRAIN RESEARCH (2014)
Subcellular distribution and early signalling events of P2X7 receptors from mouse cerebellar granule neurons
Jesus Sanchez-Nogueiro et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Adenosine Receptors: Expression, Function and Regulation
Sandeep Sheth et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Antidepressant-like effect of ascorbic acid is associated with the modulation of mammalian target of rapamycin pathway
Morgana Moretti et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2014)
MAPK signaling correlates with the antidepressant effects of ketamine
Gislaine Z. Reus et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2014)
PROTECTION BY INOSINE IN A CELLULAR MODEL OF PARKINSON'S DISEASE
S. Cipriani et al.
NEUROSCIENCE (2014)
Involvement of PKA, PKC, CAMK-II and MEK1/2 in the acute antidepressant-like effect of creatine in mice
Mauricio P. Cunha et al.
PHARMACOLOGICAL REPORTS (2014)
Antidepressant activity of the adenosine A2A receptor antagonist, istradefylline (KW-6002) on learned helplessness in rats
Koji Yamada et al.
PSYCHOPHARMACOLOGY (2014)
Emerging role of CaMKII in neuropsychiatric disease
A. J. Robison
TRENDS IN NEUROSCIENCES (2014)
Oral administration of inosine produces antidepressant-like effects in mice
Junko Muto et al.
SCIENTIFIC REPORTS (2014)
Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease A Randomized Clinical Trial
Michael A. Schwarzschild et al.
JAMA NEUROLOGY (2014)
Overexpression of adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety
Joana E. Coelho et al.
FRONTIERS IN PSYCHIATRY (2014)
The role of ERK1/2 in the regulation of proliferation and differentiation of astrocytes in developing brain
Peipei Cheng et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2013)
Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects
Vanja Duric et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
Vatairea macrocarpa Lectin (VML) Induces Depressive-like Behavior and Expression of Neuroinflammatory Markers in Mice
Filipe Marques Goncalves et al.
NEUROCHEMICAL RESEARCH (2013)
Synaptic plasticity in depression: Molecular, cellular and functional correlates
W. N. Marsden
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2013)
Role of pertussis toxin-sensitive G-protein, K+ channels, and voltage-gated Ca2+ channels in the antinociceptive effect of inosine
Sergio Jose Macedo-Junior et al.
PURINERGIC SIGNALLING (2013)
The antidepressant-like effect of inosine in the FST is associated with both adenosine A1 and A2A receptors
Manuella P. Kaster et al.
PURINERGIC SIGNALLING (2013)
P2X Receptors as Drug Targets
R. Alan North et al.
MOLECULAR PHARMACOLOGY (2013)
Serum uric acid levels and the clinical characteristics of depression
Shenglin Wen et al.
CLINICAL BIOCHEMISTRY (2012)
Staging methods for treatment resistant depression. A systematic review
Henricus G. Ruhe et al.
JOURNAL OF AFFECTIVE DISORDERS (2012)
Depressive-like behavior induced by tumor necrosis factor-alpha in mice
Manuella P. Kaster et al.
NEUROPHARMACOLOGY (2012)
Involvement of PKA, CaMKII, PKC, MAPK/ERK and PI3K in the acute antidepressant-like effect of ferulic acid in the tail suspension test
Ana Lucia Bertarello Zeni et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2012)
Ketamine plus imipramine treatment induces antidepressant-like behavior and increases CREB and BDNF protein levels and PKA and PKC phosphorylation in rat brain
Gislaine Z. Reus et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Neuroprotective signaling pathways are modulated by adenosine in the anoxia tolerant turtle
Gauri H. Nayak et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)
Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia
Peixiong Yuan et al.
JOURNAL OF AFFECTIVE DISORDERS (2010)
Inosine Reduces Pain-Related Behavior in Mice: Involvement of Adenosine A1 and A2A Receptor Subtypes and Protein Kinase C Pathways
Francisney P. Nascimento et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Nucleoside Map of the Human Central Nervous System
Zsolt Kovacs et al.
NEUROCHEMICAL RESEARCH (2010)
Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?
Xiaohua Li et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Akt/GSK3 Signaling in the Action of Psychotropic Drugs
Jean-Martin Beaulieu et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2009)
The Treatment of Multiple Sclerosis with Inosine
Clyde E. Markowitz et al.
JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE (2009)
Enhancing Brain Adenosine Signaling With the Nucleoside Transport Blocker NBTI (S-(4-Nitrobenzyl)-6-Theoinosine) Mimics the Effects of Inescapable Shock on Later Shuttle-Escape Performance in Rats
Thomas R. Minor et al.
BEHAVIORAL NEUROSCIENCE (2008)
Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression
Shannon L. Gourley et al.
BIOLOGICAL PSYCHIATRY (2008)
The molecular neurobiology of depression
Vaishnav Krishnan et al.
NATURE (2008)
Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice
Angelo O. Rosa et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2008)
A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment
Catharine H. Duman et al.
BIOLOGICAL PSYCHIATRY (2007)
Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells
Michael F. Ethier et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)
Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice
RC Almeida et al.
NEUROSCIENCE LETTERS (2006)
Adenosine receptors as therapeutic targets
KA Jacobson et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Inosine reduces ischemic brain injury in rats
H Shen et al.
STROKE (2005)
Immunomodulatory and neuroprotective effects of inosine
G Haskó et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
Adenosine administration produces an antidepressant-like effect in mice:: evidence for the involvement of A1 and A2A receptors
MP Kaster et al.
NEUROSCIENCE LETTERS (2004)
Focus on CaMKII: a molecular switch in the pathophysiology and treatment of mood and anxiety disorders
J Du et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2004)
G16-mediated activation of nuclear factor κB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling
AMF Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Antidepressants activate CaMKII in neuron cell body by Thr286 phosphorylation
E Tiraboschi et al.
NEUROREPORT (2004)
Differential requirement for A2a and A3 adenosine receptors for the protective effect of inosine in vivo
G Gomez et al.
BLOOD (2003)
Effects of inosine on axonal regeneration of axotomized retinal ganglion cells in adult rats
MM Wu et al.
NEUROSCIENCE LETTERS (2003)
Selective regulation of presynaptic calcium/calmodulin-dependent protein kinase II by psychotropic drugs
E Celano et al.
BIOLOGICAL PSYCHIATRY (2003)
Inosine induces axonal rewiring and improves behavioral outcome after stroke
P Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Antidepressants and neuroplasticity
C D'Sa et al.
BIPOLAR DISORDERS (2002)
Ten years of protein kinase B signalling: a hard Akt to follow
DP Brazil et al.
TRENDS IN BIOCHEMICAL SCIENCES (2001)