4.6 Review

Structural aspects of HDAC8 mechanism and dysfunction in Cornelia de Lange syndrome spectrum disorders

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

General Base-General Acid Catalysis in Human Histone Deacetylase 8

M. Lucy Gantt et al.

BIOCHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening

Ahmed M. O. Elbatsh et al.

MOLECULAR CELL (2016)

Article Biochemistry & Molecular Biology

Releasing Activity Disengages Cohesin's Smc3/Scc1 Interface in a Process Blocked by Acetylation

Frederic Beckouet et al.

MOLECULAR CELL (2016)

Article Biochemistry & Molecular Biology

Histone deacetylase 6 structure and molecular basis of catalysis and inhibition

Yang Hai et al.

NATURE CHEMICAL BIOLOGY (2016)

Article Multidisciplinary Sciences

KDAC8 with High Basal Velocity Is Not Activated by N-Acetylthioureas

Tasha B. Toro et al.

PLOS ONE (2016)

Article Biochemistry & Molecular Biology

Variable Active Site Loop Conformations Accommodate the Binding of Macrocyclic Largazole Analogues to HDAC8

Christophe Decroos et al.

BIOCHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Mechanism of N-Acylthiourea-mediated Activation of Human Histone Deacetylase 8 (HDAC8) at Molecular and Cellular Levels

Raushan K. Singh et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Review Genetics & Heredity

Cornelia de Lange syndrome

M. I. Boyle et al.

CLINICAL GENETICS (2015)

Article Biochemistry & Molecular Biology

Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders

Christophe Decroos et al.

ACS CHEMICAL BIOLOGY (2014)

Article Genetics & Heredity

Exome sequencing identifies a de novo mutation in HDAC8 associated with Cornelia de Lange syndrome

Lei Feng et al.

JOURNAL OF HUMAN GENETICS (2014)

Article Multidisciplinary Sciences

Closing the cohesin ring: Structure and function of its Smc3-kleisin interface

Thomas G. Gligoris et al.

SCIENCE (2014)

Article Cell Biology

Cohesin, a chromatin engagement ring

Silvia Remeseiro et al.

CURRENT OPINION IN CELL BIOLOGY (2013)

Article Multidisciplinary Sciences

Pds5 promotes and protects cohesin acetylation

Kok-Lung Chan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Cohesin's DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation

Kok-Lung Chan et al.

Article Multidisciplinary Sciences

HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

Matthew A. Deardorff et al.

NATURE (2012)

Article Chemistry, Medicinal

On the function of the internal cavity of histone deacetylase protein 8: R37 is a crucial residue for catalysis

Shozeb Haider et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)

Article Biochemistry & Molecular Biology

Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes

Patrick M. Lombardi et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2011)

Article Chemistry, Multidisciplinary

Structural Basis of the Antiproliferative Activity of Largazole, a Depsipeptide Inhibitor of the Histone Deacetylases

Kathryn E. Cole et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Genetics & Heredity

Facial Diagnosis of Mild and Variant CdLS: Insights From a Dysmorphologist Survey

Sarika Rohatgi et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2010)

Article Biochemistry & Molecular Biology

Activation and Inhibition of Histone Deacetylase 8 by Monovalent Cations

Stephanie L. Gantt et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

An Smc3 Acetylation Cycle Is Essential for Establishment of Sister Chromatid Cohesion

Frederic Beckouet et al.

MOLECULAR CELL (2010)

Article Multidisciplinary Sciences

On the Molecular Etiology of Cornelia de Lange Syndrome

Dale Dorsett et al.

YEAR IN HUMAN AND MEDICAL GENETICS 2009 (2009)

Review Genetics & Heredity

Cohesin: Its Roles and Mechanisms

Kim Nasmyth et al.

ANNUAL REVIEW OF GENETICS (2009)

Review Genetics & Heredity

Cornelia de Lange syndrome, cohesin, and beyond

J. Liu et al.

CLINICAL GENETICS (2009)

Article Cell Biology

Epigenetic control of skull morphogenesis by histone deacetylase 8

Michael Haberland et al.

GENES & DEVELOPMENT (2009)

Article Genetics & Heredity

Descriptive epidemiology of Cornelia de Lange syndrome in Europe

Ingeborg Barisic et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2008)

Review Biochemistry & Molecular Biology

Evolution of the arginase fold and functional diversity

D. P. Dowling et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Article Biochemistry & Molecular Biology

Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast

Jinglan Zhang et al.

MOLECULAR CELL (2008)

Article Multidisciplinary Sciences

A molecular determinant for the establishment of sister chromatid cohesion

Elcin Unal et al.

SCIENCE (2008)

Article Multidisciplinary Sciences

Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion

Tom Rolef Ben-Shahar et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex

Alessandro Vannini et al.

EMBO REPORTS (2007)

Review Chemistry, Multidisciplinary

Arginase: Structure, mechanism, and physiological role in male and female sexual arousal

DW Christianson

ACCOUNTS OF CHEMICAL RESEARCH (2005)

Article Biochemistry & Molecular Biology

Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases

JR Somoza et al.

STRUCTURE (2004)

Article Biochemistry & Molecular Biology

Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates

D Riester et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Multidisciplinary Sciences

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

A Vannini et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Chromosomal cohesin forms a ring

S Gruber et al.