Related references
Note: Only part of the references are listed.Dynamic tubulation of mitochondria drives mitochondrial network formation
Chong Wang et al.
CELL RESEARCH (2015)
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
Yu-Chiang Lai et al.
EMBO JOURNAL (2015)
The Organization of Mitochondrial Quality Control and Life Cycle in the Nervous System In Vivo in the Absence of PINK1
Swathi Devireddy et al.
JOURNAL OF NEUROSCIENCE (2015)
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
Jin-Mi Heo et al.
MOLECULAR CELL (2015)
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Michael Lazarou et al.
NATURE (2015)
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson's Disease
Alicia M. Pickrell et al.
NEURON (2015)
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
Agne Kazlauskaite et al.
BIOCHEMICAL JOURNAL (2014)
Glucose Regulates Mitochondrial Motility via Milton Modification by O-GlcNAc Transferase
Gulcin Pekkurnaz et al.
CELL (2014)
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
Gian-Luca McLelland et al.
EMBO JOURNAL (2014)
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
Tom Cornelissen et al.
HUMAN MOLECULAR GENETICS (2014)
Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase
Nicol Birsa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
Ghazaleh Ashrafi et al.
JOURNAL OF CELL BIOLOGY (2014)
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Lesley A. Kane et al.
JOURNAL OF CELL BIOLOGY (2014)
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
Alban Ordureau et al.
MOLECULAR CELL (2014)
Ubiquitin is phosphorylated by PINK1 to activate parkin
Fumika Koyano et al.
NATURE (2014)
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
Baris Bingol et al.
NATURE (2014)
Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
Yvette C. Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
Vanessa A. Morais et al.
SCIENCE (2014)
PINK1-mediated Phosphorylation of Miro Inhibits Synaptic Growth and Protects Dopaminergic Neurons in Drosophila
Pei-I Tsai et al.
SCIENTIFIC REPORTS (2014)
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Agne Kazlauskaite et al.
OPEN BIOLOGY (2014)
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
Koji Yamano et al.
ELIFE (2014)
PINK1 is degraded through the N-end rule pathway
Koji Yamano et al.
AUTOPHAGY (2013)
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
Seok Min Jin et al.
AUTOPHAGY (2013)
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
Xinde Zheng et al.
CELL RESEARCH (2013)
A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson's Research
Marco A. S. Baptista et al.
DISEASE MODELS & MECHANISMS (2013)
Structure of the human Parkin ligase domain in an autoinhibited state
Tobias Wauer et al.
EMBO JOURNAL (2013)
Structural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein Miro
Julian L. Klosowiak et al.
EMBO REPORTS (2013)
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
Michael Lazarou et al.
JOURNAL OF CELL BIOLOGY (2013)
The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO
Anne Kathrin Mueller-Rischart et al.
MOLECULAR CELL (2013)
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
Shireen A. Sarraf et al.
NATURE (2013)
Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
Jean-Francois Trempe et al.
SCIENCE (2013)
PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
Yun Chen et al.
SCIENCE (2013)
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
B. E. Riley et al.
NATURE COMMUNICATIONS (2013)
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
Michael Lazarou et al.
DEVELOPMENTAL CELL (2012)
Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences
Nicole Exner et al.
EMBO JOURNAL (2012)
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
Andrew W. Greene et al.
EMBO REPORTS (2012)
Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy
Eisuke Itakura et al.
JOURNAL OF CELL SCIENCE (2012)
Parkinson's Disease-Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria
Song Liu et al.
PLOS GENETICS (2012)
PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
Xinnan Wang et al.
CELL (2011)
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
Nickie C. Chan et al.
HUMAN MOLECULAR GENETICS (2011)
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
Cathrin Meissner et al.
JOURNAL OF NEUROCHEMISTRY (2011)
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
Derek P. Narendra et al.
AUTOPHAGY (2010)
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
Atsushi Tanaka et al.
JOURNAL OF CELL BIOLOGY (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Seok Min Jin et al.
JOURNAL OF CELL BIOLOGY (2010)
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
Noriyuki Matsuda et al.
JOURNAL OF CELL BIOLOGY (2010)
Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex
Albert Misko et al.
JOURNAL OF NEUROSCIENCE (2010)
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
Cristofol Vives-Bauza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Derek P. Narendra et al.
PLOS BIOLOGY (2010)
Pink1 Forms a Multiprotein Complex with Miro and Milton, Linking Pink1 Function to Mitochondrial Trafficking
Andreas Weihofen et al.
BIOCHEMISTRY (2009)
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
Vanessa A. Morais et al.
EMBO MOLECULAR MEDICINE (2009)
Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release
Alison K. Berger et al.
HUMAN MOLECULAR GENETICS (2009)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
The PINK1/Parkin pathway regulates mitochondrial morphology
Angela C. Poole et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The age of crosstalk: Phosphorylation, ubiquitination, and beyond
Tony Hunter
MOLECULAR CELL (2007)
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
Julia W. Pridgeon et al.
PLOS BIOLOGY (2007)
Parkin mediates neuroprotection through activation of IκB kinase/nuclear factor-κB signaling
Iris H. Henn et al.
JOURNAL OF NEUROSCIENCE (2007)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
Diverse effects of pathogenic mutations of parkin that catalyze multiple monoubiquitylation in vitro
N Matsuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
MS Goldberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis
Å Fransson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Share Paper
