4.8 Article

HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

Clinical and prognostic relevance of EZH2 in breast cancer: A meta-analysis

Xu Wang et al.

BIOMEDICINE & PHARMACOTHERAPY (2015)

Article Medicine, Research & Experimental

Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma

Jiro Kikuchi et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Multidisciplinary Sciences

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells

Huimin Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

EZH2 expands breast stem cells through activation of NOTCH1 signaling

Maria E. Gonzalez et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Oncology

Role of hypoxia-inducible factors in breast cancer metastasis

Daniele M. Gilkes et al.

FUTURE ONCOLOGY (2013)

Article Biochemistry & Molecular Biology

PAF and EZH2 Induce Wnt/β-Catenin Signaling Hyperactivation

Hae-Yun Jung et al.

MOLECULAR CELL (2013)

Article Biochemistry & Molecular Biology

Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer

Sakari Vanharanta et al.

NATURE MEDICINE (2013)

Meeting Abstract Oncology

A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

Jessica D. Kessler et al.

CANCER RESEARCH (2012)

Article Cell Biology

EZH2 couples pancreatic regeneration to neoplastic progression

Jon Mallen-St Clair et al.

GENES & DEVELOPMENT (2012)

Article Cell Biology

A complex Polycomb issue: the two faces of EZH2 in cancer

Hanno Hock

GENES & DEVELOPMENT (2012)

Article Oncology

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes

Karolina Holm et al.

MOLECULAR ONCOLOGY (2012)

Article Multidisciplinary Sciences

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

Michael T. McCabe et al.

NATURE (2012)

Article Multidisciplinary Sciences

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt et al.

NATURE (2012)

Article Multidisciplinary Sciences

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang et al.

NATURE (2012)

Article Multidisciplinary Sciences

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

Christina Curtis et al.

NATURE (2012)

Article Biochemistry & Molecular Biology

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

Panagiotis Ntziachristos et al.

NATURE MEDICINE (2012)

Article Multidisciplinary Sciences

Suppression of FOXM1 Sensitizes Human Cancer Cells to Cell Death Induced by DNA-Damage

Marianna Halasi et al.

PLOS ONE (2012)

Article Medicine, General & Internal

A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer

Christos Hatzis et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)

Article Biochemistry & Molecular Biology

Nucleophosmin Interacts with FOXM1 and Modulates the Level and Localization of FOXM1 in Human Cancer Cells

Uppoor G. Bhat et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers

Shuet Theng Lee et al.

MOLECULAR CELL (2011)

Article Multidisciplinary Sciences

GOBO: Gene Expression-Based Outcome for Breast Cancer Online

Markus Ringner et al.

PLOS ONE (2011)

Article Genetics & Heredity

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

Gorica Nikoloski et al.

NATURE GENETICS (2010)

Article Genetics & Heredity

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

Thomas Ernst et al.

NATURE GENETICS (2010)

Letter Cell Biology

A novel mode of FoxM1 regulation Positive auto-regulatory loop

Marianna Halasi et al.

CELL CYCLE (2009)

Article Biochemistry & Molecular Biology

Transcriptional Up-Regulation of FoxM1 in Response to Hypoxia Is Mediated by HIF-1

Li-Min Xia et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

Q. Cao et al.

ONCOGENE (2008)

Article Biochemistry & Molecular Biology

The phosphorylation status of PAS-B distinguishes HIF-1α from HIF-2α in NBS1 repression

Kenneth K. -W To et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

HIF-1α induces genetic instability by transcriptionally downregulating MutSα expression

M Koshiji et al.

MOLECULAR CELL (2005)

Article Biochemistry & Molecular Biology

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

AP Bracken et al.

EMBO JOURNAL (2003)

Article Multidisciplinary Sciences

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

CG Kleer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Repeated observation of breast tumor subtypes in independent gene expression data sets

T Sorlie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Induction of hypoxia-inducible factor-1α by transcriptional and translational mechanisms

EL Pagé et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1α-degradative pathway

JS Isaacs et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

T Sorlie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Multidisciplinary Sciences

Molecular portraits of human breast tumours

CM Perou et al.

NATURE (2000)