4.6 Article

Recent Update on Radiation Dose Assessment for the State-of-the-Art Coronary Computed Tomography Angiography Protocols

Journal

PLOS ONE
Volume 11, Issue 8, Pages -

Publisher

PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0161543

Keywords

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Funding

  1. High Impact Research Grant from the Ministry of Education, Malaysia [UM.C/625/1/HIR/MOHE/MED/36]

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Objectives This study aimed to measure the absorbed doses in selected organs for prospectively ECG-triggered coronary computed tomography angiography (CCTA) using five different generations CT scanners in a female adult anthropomorphic phantom and to estimate the effective dose (H-E). Materials and Methods Prospectively ECG-triggered CCTA was performed using five commercially available CT scanners: 64-detector-row single source CT (SSCT), 2 x 32-detector-row-dual source CT (DSCT), 2 x 64-detector-row DSCT and 320-detector-row SSCT scanners. Absorbed doses were measured in 34 organs using pre-calibrated optically stimulated luminescence dosimeters (OSLDs) placed inside a standard female adult anthropomorphic phantom. H-E was calculated from the measured organ doses and compared to the H-E derived from the air kerma-length product (P-KL) using the conversion coefficient of 0.014 mSv.mGy(-1).cm(-1) for the chest region. Results Both breasts and lungs received the highest radiation dose during CCTA examination. The highest H-E was received from 2 x 32-detector-row DSCT scanner (6.06 +/- 0.72 mSv), followed by 64-detector-row SSCT (5.60 +/- 0.68 and 5.02 +/- 0.73 mSv), 2 x 64-detector-row DSCT (1.88 +/- 0.25 mSv) and 320-detector-row SSCT (1.34 +/- 0.48 mSv) scanners. H-E calculated from the measured organ doses were about 38 to 53% higher than the H-E derived from the P-KL-to-H-E conversion factor. Conclusion The radiation doses received from a prospectively ECG-triggered CCTA are relatively small and are depending on the scanner technology and imaging protocols. H-E as low as 1.34 and 1.88 mSv can be achieved in prospectively ECG-triggered CCTA using 320-detectorrow SSCT and 2 x 64-detector-row DSCT scanners.

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