Journal
PHYTOCHEMISTRY LETTERS
Volume 17, Issue -, Pages 299-303Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2016.08.014
Keywords
Delphinium iliense; Diterpenoid alkaloids; Cytotoxicity
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Funding
- National Natural Foundation of China [31171695]
- Science and Technology Support Programs of Sichuan Province [2013SZ0083]
- Research Foundation for Educational Commission of Sichuan Province [15TD0048]
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Two new C-19-diterpenoid alkaloids, iliensines A (1) and B (2) were isolated from the entire plant of Delphinium iliense, together with eight known compounds (3-10). The structures were determined through extensive spectroscopic analyses, including 1D, 2D NMR, and HR-ESI-MS. Iliensine A (1) is the first example of a natural diterpene alkaloid containing a glucose group. Compounds 1, 2, 3, 6 and 9 were evaluated for cytotoxicity against HCT116 and HepG2 human cancer cell lines. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
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