Journal
PHYTOCHEMISTRY LETTERS
Volume 17, Issue -, Pages 232-237Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2016.08.003
Keywords
Fusarium solani; Lasiodiplodin; Endophytes; Ca2+ signaling inhibition activity
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Funding
- Grants-in-Aid for Scientific Research [15J04501] Funding Source: KAKEN
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Three novel benzenediol lactone derivatives, 7-hydroxy-14-de-O-methyl-lasiodiplodin (2), ethyl-3,5dihydroxy- 7-(6,8-dihydroxynonyl) benzoate (4), and 7-ethylbenzoate-7-heptanoic acid (5), together with known compounds, 14-de-O-methyl-lasiodiplodin (1) and ethyl-3,5-dihydroxy-7-(8-hydroxynonyl) benzoate (3), were isolated from the culture of Fusarium solani T-13, a fungus from a dead branch. Their structures were elucidated using 1D- and 2D-NMR spectroscopy. Compounds 1, 3 and 4 showed doughnut like phenotypes of growth restoring activity against the mutant yeast (zds1 Delta erg3 Delta pdr1/3 Delta) at the concentration of 0.16, 0.63 and 1.25 mg/spot, respectively. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
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