Journal
PHYSIOLOGY
Volume 31, Issue 1, Pages 16-24Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00029.2015
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Funding
- Italian Ministry of Education, University and Research (MIUR) [PON 01_02833]
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Micro-RNAs (miRNAs) are small noncoding RNAs involved in the posttranscriptional regulation of gene expression. Exosomes have recently emerged as novel elements of intercellular communication in the cardiovascular system. Exosomal miRNAs could be key players in intercellular cross-talk, particularly during different diseases such as myocardial infarction (MI) and heart failure (HF). This review addresses the functional role played by exosomal miRNAs in heart disease and their potential use as new biomarkers.
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