Journal
PHYSICS-USPEKHI
Volume 59, Issue 5, Pages 487-501Publisher
TURPION LTD
DOI: 10.3367/UFNe.2015.12.037734
Keywords
optical bioimaging; biophotonics; optical coherence tomography; fluorescent microscopy; optical nanoscopy; optoacoustics; optical diffusion tomography; fluorescent agents; fluorescent proteins; upconversion nanoparticles; STED; STORM
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Optical bioimaging methods have a wide range of applications in the life sciences, most notably including the molecular resolution study of subcellular structures, small animal molecular imaging, and structural and functional clinical diagnostics of tissue layers and organs. We review fluorescent microscopy, fluorescent macroscopy, optical coherence tomography, optoacoustic tomography, and optical diffuse spectroscopy and tomography from the standpoint of physical fundamentals, applications, and progress.
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