Journal
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Volume 18, Issue 21, Pages 14182-14185Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cp00420b
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Funding
- National Institute On Aging [NIH R15AG038977]
- ACS-PRF [47244-G4]
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The fluorescence of BODIPY and click-BODIPY dyes was found to substantially increase in the presence of bovine serum albumin (BSA). BSA acted as a solubilizer for dye aggregates, in addition to being a conventional binding scaffold for the click-BODIPY dyes, indicating that disaggregation of fluorophores should be considered when evaluating dye-protein interactions.
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