4.2 Article

ANALGESIC EFFECT OF SEVERAL NONSTEROIDAL ANTI-INFLAMMATORY DRUG NANOAEROSOLS

Journal

PHARMACEUTICAL CHEMISTRY JOURNAL
Volume 49, Issue 10, Pages 680-682

Publisher

SPRINGER
DOI: 10.1007/s11094-016-1352-y

Keywords

nonsteroidal anti-inflammatory drugs; nanoaerosols; indomethacin; butadion; diclofenac

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The analgesic activities of nanoaerosols of the nonsteroidal anti-inflammatory drugs indomethacin, butadion, and diclofenac were studied. It was found that nanoaerosol delivery of these drugs gave analgesic activities that were comparable to those of oral delivery 5 - 8 min after administration at doses that were 3 - 5 orders of magnitude lower.

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