Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 22, Issue 10, Pages 3210-3223Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201504036
Keywords
fluorination; fluoroalkylation; ketones; one-pot synthesis; rearrangement
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Funding
- National Basic Research Program of China [2015CB931900, 2012CB821600]
- NNSF of China [21372246, 21421002, 21302206, 21402227]
- Shanghai City [15XD1504400]
- Chinese Academy of Sciences
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Fluorinated ketones are intriguing compounds in synthetic chemistry and life science-related fields. The development of efficient methodologies to obtain these compounds is of significant importance and has therefore attracted considerable attention. This Minireview highlights recent progress made in the synthesis of fluorine-containing ketones, with an emphasis on those methods in which the construction of carbonyl groups is synergetic with distal (-, -, -, etc.) incorporation of fluorine atoms or fluorinated groups.
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