Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 21, Issue 25, Pages 9003-9007Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201500816
Keywords
asymmetric catalysis; oxabenzonorbornadienes; phenols; ring-opening reaction; syn-stereoselectivity
Categories
Ask authors/readers for more resources
A new palladium/zinc co-catalyst system associated with chiral (R)-Difluorphos for asymmetric ring-opening reaction of oxabenzonorbornadienes with phenols is reported. This catalyst system allows the formation of cis-2-aryloxy-1,2-dihydronaphthalen-1-ol products in good yields (up to 95% yield) with excellent enantioselectivities (up to 99% ee). The cis-configuration of the product has been confirmed by X-ray crystal structure analysis. To the best of our knowledge, it represents the first example in ring-opening reactions of bicycloalkenes with heteronucleophiles in a syn-stereoselective manner.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available