Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 21, Issue 33, Pages 11644-11657Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201500869
Keywords
asymmetric catalysis; axial chirality; biaryls; dynamic kinetic resolution; kinetic resolution
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Funding
- North Dakota State University
- [NSF-CHM-0709061]
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Biaryl compounds with axial chirality are very common in synthetic chemistry, especially in catalysis. Axially chiral biaryls are important due to their biological activities and extensive applications in asymmetric catalysis. Thus the development of efficient enantioselective methods for their synthesis has attracted considerable attention. This Minireview discusses the progress made in catalytic kinetic resolution of biaryl compounds and chronicles significant advances made recently in catalytic kinetic resolution of biaryl scaffolds.
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