Journal
PARASITOLOGY
Volume 144, Issue 3, Pages 316-326Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0031182016000342
Keywords
Strongyloides spp; genetics; parthenogenesis; sexual reproduction; sex determination
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Funding
- Max Planck Society
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Classical and reverse genetics remain invaluable tools for the scientific investigation of model organisms. Genetic analysis of endoparasites is generally difficult because the sexual adults required for crossing and other manipulations are usually hidden within their host. Strongyloides spp. and Parastrongyloides spp. are notable exceptions to this and their free-living adults offer unique opportunities to manipulate these parasites experimentally. Here I review the modes of inheritance in the two generations of Strongyloides/Parastrongyloides and I discuss the opportunities and the limitations of the currently available methodology for the genetic analysis of these two genera.
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