Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 20, Issue 2, Pages 140-177Publisher
AMER CHEMICAL SOC
DOI: 10.1021/op500305s
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This review showcases various coupling reagents which have been implemented specifically for large-scale amide synthesis via the condensation of an acid and amine, while highlighting the benefits and drawbacks of each reagent on an industrial scale.
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