Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 20, Issue 7, Pages 1134-1147Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.oprd.6b00125
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Funding
- NIH [GM096129]
- Eli Lilly
- Camille and Henry Dreyfus Foundation
- University of Michigan
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Photoredox catalysis has emerged as a powerful tool for the synthetic chemist to access challenging targets and to generate new structural complexity. This review focuses on the application of this mode of catalysis to arrive at known pharmaceutically active compounds. Within this setting the growing synergy with other modes of catalysis, such as nickel/photoredox dual catalysis, as well as pioneering examples utilizing continuous flow to transition photoredox catalysis to preparative scale will be highlighted.
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