Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 20, Issue 2, Pages 409-413Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.oprd.5b00354
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Funding
- Innovative Medicines Initiative Grant [115489]
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Two conformationally restricted three-dimensional aminoketone scaffolds have been synthesized in only three steps, using a continuous flow photochemistry approach, which is also amenable to scale-up. In addition, several approaches to further derivatize these scaffolds for the synthesis of low molecular weight compound libraries have been detailed.
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