4.8 Article

Cobalt(II)-Catalyzed C-H Amination of Arenes with Simple Alkylamines

Journal

ORGANIC LETTERS
Volume 18, Issue 6, Pages 1318-1321

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00241

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Funding

  1. Natural Science Foundation of China [21272217, 21502173]

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A new method of cobalt-catalyzed amination of arylamides with simple alkylamines is reported through C(sp(2))-H bond functionalization. For the first time, inexpensive cobalt is exploited as the catalyst in the amination of C(sp(2))-H bond using simple alkylamines.

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