Double Chiral Induction Enables a Stereoselective Carbonyl Allylation with Simple Alkenes under the Sequential Catalysis of Palladium Complex and Chiral Phosphoric Acid

An enantioselective carbohyl allylation of aldehydes with simple alkenes has been achieved via a one-pot protocol. consisting of a Pd-catalyzed allyic C-H borylation with. bis(pinanediolato)diboron and a chiral Bronsted acid catalyzed asymmetric allylborylation, delivering homoallylic alcohols in High yield's and with excellent diastereo- and enantioseledivities. The double chiral induction of chiral allylic borate and chiral phosphoric acid allows the reaction to give excellent. stereoselectivities.