Journal
ORGANIC LETTERS
Volume 18, Issue 23, Pages 6144-6147Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b03155
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Funding
- NSFC [21525208, 21472186]
- Dalian Institute of Chemical Physics (CAS)
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDB 17020300]
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Quinazoline N-oxides have been prepared from simple ketoximes and 1,4,2-dioxazol-5-ones via Rh(III)-catalyzed C-H activation amidation of the ketoximes and subsequent Zn(II)-catalyzed cyclization. The substrate scope and functional group compatibility were examined. The reaction features relay catalysis by Rh(III) and Zn(II).
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