Journal
ORGANIC LETTERS
Volume 18, Issue 3, Pages 508-511Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b03545
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The first described reaction between N-tosylhydrazone and SO2 is reported to provide alkyl sulfonamides in the presence of various amines. In this procedurally simple method, hydrazones of both unsaturated aldehydes and ketones proceed in moderate to excellent yields. Primary and secondary aliphatic amines are accommodated in this reaction, which provides a novel route to sulfonamides.
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