Journal
ORGANIC LETTERS
Volume 18, Issue 7, Pages 1638-1641Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00487
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Lewis acid catalyzed Passerini reactions on chiral aldehydes derived from desymmetrized erythritol take place with unprecedented diastereoselectivity. The resulting adducts have been selectively and efficiently converted into a variety of densely functionalized, polyoxygenated heterocycles.
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