Journal
ORGANIC LETTERS
Volume 18, Issue 21, Pages 5740-5743Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b03005
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Funding
- NNSFC [21472122, 21272147, 81202465, 81573354]
- National Key Technologies R&D Program for New Drugs of China [2012ZX09301003]
- Shanghai Pujiang Program [16PJD024]
- State Key Laboratory of Applied Organic Chemistry (Lanzhou University)
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The first water-soluble biphen[4]arene containing eight carboxylato moieties (carboxylatobiphen[4]arene, CBP4) has been synthesized. Selective molecular recognition of acetylcholine (ACh) against choline (Ch) and betaine (Bt) and pH-responsive host-guest complexation in aqueous media are described.
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