Journal
ORGANIC LETTERS
Volume 18, Issue 8, Pages 1916-1919Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00749
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Funding
- National Natural Science Foundation of China [21272148, 21472121, 21272147]
- State Key Laboratory of Applied Organic Chemistry
- Lanzhou University
- Shanghai Key Laboratory of High Temperature Superconductors [14DZ2260700]
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A TBAI (tetrabutylammonium iodide)-catalyzed direct alpha-oxyacylation of carbonyl compounds from readily available toluene derivatives has been developed. The distinguished features of this metal-free protocol include the employment of simple starting material, a wide carbonyl compound scope, and mild reaction conditions.
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