4.8 Article

N-Heterocyclic Carbene-Catalyzed Convenient Benzonitrile Assembly

Journal

ORGANIC LETTERS
Volume 18, Issue 9, Pages 2212-2215

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00844

Keywords

-

Funding

  1. Thousand Plan program
  2. Bayer Investigator Fellow
  3. Tsinghua-Peking Centre for Life Sciences (CLS)
  4. Tsinghua University

Ask authors/readers for more resources

The benzonitrile unit is widely found in natural products, pharmaceuticals, and agrochemicals. Synthesis of benzonitriles has received considerable interests from the chemical community over the last few decades. Present synthetic protocols mainly rely on the pre-existing benzene core to install a cyano moiety. A new NHC-catalyzed [4 + 2]-enzannulation protocol is reported to assemble the benzonitrile framework.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available