Journal
ORGANIC LETTERS
Volume 19, Issue 1, Pages 94-97Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b03356
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Funding
- National Natural Science Foundation of China [21390400, 21520102003, 21272180, 21302148]
- Hubei Province Natural Science Foundation of China [2013CFA081]
- Research Fund for the Doctoral Program of Higher Education of China [20120141130002]
- Ministry of Science and Technology of China [2012YQ120060]
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An efficient palladium/copper CO-catalyzed oxidative double C(sp(2))-H functionalization/carbonylation of diphenyl-amines for synthesis of acridones has been developed. This method utilizes readily available starting materials :and mild reaction conditions. The protocol provides a simple; efficient, and atom economic way to access acridones. Notably the present protocol has excellent functional group tolerance and application value.
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