Journal
ORGANIC LETTERS
Volume 18, Issue 24, Pages 6232-6235Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b02710
Keywords
-
Categories
Funding
- National Key Research and Development Program of China [2016YFA0602900]
- National Natural Science Foundation of China [21472051, 21420102003, 21490572]
- Pearl River S&T Nova Program of Guangzhou [201610010160]
Ask authors/readers for more resources
The vinyl moiety-assisted selective O-nucleopalladation is reported, which offers rapid constructions of cycloolefins and cyclopropanes via oxidant-induced cyclization of enynes. O-2 resulted in the unexpected 6-endo-Heck cyclization, while CuCl2 led to a 5-exo-trig pathway and synergetic S(N)2-type C-C bond formation. Amide works as an O-transferred nucleophilic group to activate the alkyne moiety, which induced divergent annulation processes. Moreover, the regenerated amides could be used for further modifications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available