4.8 Article

Amination of 3-Substituted Benzofuran-2(3H)-ones Triggered by Single-Electron Transfer

Journal

ORGANIC LETTERS
Volume 18, Issue 5, Pages 1036-1039

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00163

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Funding

  1. Foundation for Specially-Appointed Professors at the National University of Defense Technology
  2. Natural Science Foundation [21390400, 21421062]
  3. Natural Science Foundation of Tianjin at Nankai University [12JCYBJC31100]

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An efficient amination reaction of 3-substituted benzofuran-2(3H)-ones promoted by cesium carbonate was developed. A putative mechanism involving a single-electron-transfer event was proposed, which represents a new reactivity for benzofuran-2(3H)-ones.

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