4.6 Article

Rhodium-catalyzed asymmetric ring opening reaction of oxabenzonorbornadienes with amines using ZnI2 as the activator

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 8, Pages 2480-2486

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob02331a

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Funding

  1. National Natural Science Foundation of China [21362043, 21162040, 21302162, 21572198]
  2. Government of Yunnan Province [2012FB170]

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The complex of [Rh(COD)Cl](2) and (R,R)-BDPP was used as an effective catalyst for the asymmetric ring opening reaction of oxabenzonorbornadienes with various amines by employing ZnI2 as the activator. Under the optimized reaction conditions, high enantioselectivities with good yields could be obtained from a wide scope of oxabenzonorbornadienes and amines.

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