Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 40, Pages 9485-9489Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob01799a
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As a part of our ongoing synthetic quest to expand the frontiers of contemporary medicinal chemistry, we now report an expedient synthesis of a potentially useful bicyclo[1.1.1]pentane building block, 3-(pyrazin-2-yl)bicyclo[1.1.1]pentane-1-carboxylic acid. This report also showcases the application of this motif as a probe in a biological study.
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