4.6 Article

Thermal 1,3-dipolar cycloaddition reaction of azomethine imines with active esters

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 28, Pages 6757-6761

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob01095d

Keywords

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Funding

  1. NSFC [21125207, 21372103, 21472079, 21572088]
  2. SRFDP [20130211110018]
  3. [IRT_15R28]

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An efficient method for the 1,3-dipolar cycloaddition of azomethine imines with active esters under thermal conditions has been described in good to high yields. This method offers a straightforward pathway to synthesize bioactive pyrazolidinones.

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