Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 20, Pages 4571-4575Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob00756b
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Funding
- Chinese University of Hong Kong Direct Grant [4053157]
- National University of Singapore [143-000-605-112]
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A trifluoroacetic acid catalyzed highly 6-endo regioselective bromocyclization of styrene-type carboxylic acid has been developed. The resulting 3,4-dihydroisocoumarines are valuable building blocks in organic synthesis.
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