4.6 Article

A molecular receptor for zwitterionic phenylalanine

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 16, Pages 3906-3912

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob00490c

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Funding

  1. University of Salamanca
  2. Spanish Ministerio de Educacion

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The combination of a 1,3-ketoenol system and two pyridine molecules attached as sulfonamide and carboxamide to a benzofuran skeleton allows the preparation of a novel chiral receptor for zwitterionic phenylalanine association. Interestingly, no crown-ether, urea or guanidinium are necessary to carry out the extraction of amino acids from the aqueous solution, which constitutes a breakthrough in comparison with other receptors for zwitterionic amino acid extraction.

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