4.6 Article

A combined computational and experimental investigation of the oxidative ring-opening of cyclic ethers by oxoammonium cations

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 16, Pages 3883-3888

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob00347h

Keywords

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Funding

  1. National Science Foundation CAREER Award [CHE-0847262]
  2. University of Connecticut Office of Undergraduate Research

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The propensity of oxoammonium cations to facilitate the oxidative ring-opening of cyclic ethers to their corresponding distal hydroxy ketones is investigated. The reaction has been evaluated using experimental and computational methods to gain deeper insight into trends in reactivity.

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