Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 14, Issue 43, Pages 10185-10188Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ob01649a
Keywords
-
Categories
Funding
- National Science Foundation of China [21502054]
- East China Normal University (ECNU)
Ask authors/readers for more resources
By using a diaryliodonium salt as a benzyne precursor, a transition metal-free approach for N-arylation of secondary amides is developed. This novel benzyne precursor, which can be prepared easily by a one step process from an aryl iodide, shows different reactivities with previous benzyne precursors in the N-arylation reaction. Mechanistic studies confirm the involvement of benzyne species (generated in situ from the diaryliodonium salts) as key intermediates.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available