Related references
Note: Only part of the references are listed.Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas
Audrey Bouillez et al.
CANCER RESEARCH (2016)
MUC1-C Stabilizes MCL-1 in the Oxidative Stress Response of Triple-Negative Breast Cancer Cells to BCL-2 Inhibitors
Masayuki Hiraki et al.
SCIENTIFIC REPORTS (2016)
Intracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle Formulation
Masanori Hasegawa et al.
CLINICAL CANCER RESEARCH (2015)
MUC1-C activates the TAK1 inflammatory pathway in colon cancer
H. Takahashi et al.
ONCOGENE (2015)
Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer
Masayuki Hiraki et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2015)
MUC1-C Induces the LIN28B -> LET-7 -> HMGA2 Axis to Regulate Self-Renewal in NSCLC
Maroof Alam et al.
MOLECULAR CANCER RESEARCH (2015)
Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target
Deepak Raina et al.
PLOS ONE (2015)
A Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage Response
Xiaozeng Lin et al.
BIOMOLECULES (2015)
Targeting the Oncogenic MUC1-C Protein Inhibits Mutant EGFR-Mediated Signaling and Survival in Non-Small Cell Lung Cancer Cells
Akriti Kharbanda et al.
CLINICAL CANCER RESEARCH (2014)
Self-renewal as a therapeutic target in human colorectal cancer
Antonija Kreso et al.
NATURE MEDICINE (2014)
Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells
D. Raina et al.
ONCOGENE (2014)
MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition
H. Rajabi et al.
ONCOGENE (2014)
Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells
Maroof Alam et al.
ONCOTARGET (2014)
MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells
Akriti Kharbanda et al.
ONCOTARGET (2014)
The regulation of Hox gene expression during animal development
Moises Mallo et al.
DEVELOPMENT (2013)
A Positive Feedback Loop Regulates the Expression of Polycomb Group Protein BMI1 via WNT Signaling Pathway
Joon-Ho Cho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
MUC1-C Oncoprotein Activates ERK→C/EBPβ Signaling and Induction of Aldehyde Dehydrogenase 1A1 in Breast Cancer Cells
Maroof Alam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The epigenetics of epithelial-mesenchymal plasticity in cancer
Wai Leong Tam et al.
NATURE MEDICINE (2013)
MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches
D. W. Kufe
ONCOGENE (2013)
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
Jianjiong Gao et al.
SCIENCE SIGNALING (2013)
Polycomb genes and cancer: Time for clinical application?
Francesco Crea et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2012)
MUC1-C Oncoprotein Induces TCF7L2 Transcription Factor Activation and Promotes Cyclin D1 Expression in Human Breast Cancer Cells
Hasan Rajabi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer
Karim Nacerddine et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Role of BMI1, a Stem Cell Factor, in Cancer Recurrence and Chemoresistance: Preclinical and Clinical Evidences
Hifzur Rahman Siddique et al.
STEM CELLS (2012)
Cancer Stem Cell Marker Bmi-1 Expression is Associated with Basal-like Phenotype and Poor Survival in Breast Cancer
Yanyang Wang et al.
WORLD JOURNAL OF SURGERY (2012)
Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity
Mitsuhiro Endoh et al.
PLOS GENETICS (2012)
MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas
Ruimin Huang et al.
FASEB JOURNAL (2011)
BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair
Vasudeva Ginjala et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Roles of the Polycomb group proteins in stem cells and cancer
H. Richly et al.
CELL DEATH & DISEASE (2011)
Identification and Characterization of Bmi-1-responding Element within the Human p16 Promoter
Sha Meng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Eaten alive: a history of macroautophagy
Zhifen Yang et al.
NATURE CELL BIOLOGY (2010)
Repression of BMI1 in normal and leukemic human CD34+ cells impairs self-renewal and induces apoptosis
Aleksandra Rizo et al.
BLOOD (2009)
Functional targeting of the MUC1 oncogene in human cancers
Donald W. Kufe
CANCER BIOLOGY & THERAPY (2009)
MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor-κB p65 Transcription Factor
Rehan Ahmad et al.
CANCER RESEARCH (2009)
Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
Yohei Shimono et al.
CELL (2009)
The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
Li-Bing Song et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Bmi1 regulates mitochondrial function and the DNA damage response pathway
Jie Liu et al.
NATURE (2009)
Mucins in cancer: function, prognosis and therapy
Donald W. Kufe
NATURE REVIEWS CANCER (2009)
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak et al.
NATURE REVIEWS CANCER (2009)
Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity
Motoaki Ohtsubo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
MUC1 oncoprotein activates the IκB kinase β complex and constitutive NF-κB signalling
Rehan Ahmad et al.
NATURE CELL BIOLOGY (2007)
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
Adrian P. Bracken et al.
GENES & DEVELOPMENT (2007)
Role of Bmi1 in H2A ubiquitylation and Hox gene silencing
Jianhua Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
R Cao et al.
MOLECULAR CELL (2005)
MUC1 oncoprotein blocks glycogen synthase kinase 3β-mediated phosphorylation and degradation of β-catenin
L Huang et al.
CANCER RESEARCH (2005)
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
J Campisi
CELL (2005)
Stem colls and cancer: The polycomb connection
ME Valk-Lingbeek et al.
CELL (2004)
Bmi1, stem cells, and senescence regulation
IK Park et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation
M de Napoles et al.
DEVELOPMENTAL CELL (2004)
Role of histone H2A ubiquitination in polycomb silencing
HB Wang et al.
NATURE (2004)
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
J Lessard et al.
NATURE (2003)