Journal
OCULAR IMMUNOLOGY AND INFLAMMATION
Volume 26, Issue 4, Pages 496-503Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/09273948.2016.1195000
Keywords
Endogenous; endophthalmitis; infectious; vitrectomy
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Funding
- NEI NIH HHS [T32 EY007145] Funding Source: Medline
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Purpose: To study the clinical features of endogenous endophthalmitis (EE) in sample patient populations from the USA and South Korea over an 8-year period.Methods: We reviewed data from 128 eyes of 60 American and 48 Korean patients diagnosed with EE and compared their clinical characteristics.Results: Fungemia and liver abscess were the most common extraocular infection sources among American (26.7%) and Korean patients (33.3%), respectively. Klebsiella pneumoniae and Candida species were the most common pathogens of EE in the Korean and the American patients, respectively. Endophthalmitis caused by fungi had a better visual prognosis than that caused by bacteria (p = 0.001). Vitrectomy was beneficial for eyes with EE due to virulent bacteria presenting with worse than counting finger vision.Conclusions: The predisposing conditions and responsible organisms for EE vary in different regions of the world. The visual prognosis was strongly influenced by the underlying pathogen.
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