Journal
NUTRITION RESEARCH
Volume 36, Issue 12, Pages 1415-1422Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.nutres.2016.11.010
Keywords
Bilberries; Lipid profile; Cardiovascular diseases risk; Biochemical parameters; Healthy participants
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Funding
- Scientific Grant Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic [1/0127/14]
- project ITEBIO Support and innovations of a special and organic products Technologies for human healthy nutrition [ITMS 26220220115]
- FCT/MEC through national funds [FCT UID/QUI/00062/2013]
- FEDER, within PT2020 Partnership Agreement
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Cardiovascular diseases (CVDs) are the leading causes of death, and lifestyle modification, including dietary changes, is recommended to improve this condition. In this study, regular consumption of bilberries was hypothesized to have beneficial effects on CVD risk reduction, by changes in human health indicators such as decreasing low-density lipoprotein cholesterol (LDL-C) and triglycerides (TGs) and increasing high-density lipoprotein cholesterol (HDL-C). The research involved women (n = 25) and men (n = 11) who consumed 150 g of frozen stored bilberries 3 times a week for 6 weeks. Anthropometric parameters, blood pressure, lipid profile, glucose, liver enzymes, creatinine, albumin, magnesium, and antiradical activity were measured. Except for the body mass index of women (P =.019), no significant changes were found for anthropometric indicators. The consumption of bilberries led to a decrease in the following parameters: total cholesterol (P = .017), LDL-C (P = .0347), TG (P = .001), glucose (P = .005), albumin (P = .001), gamma-glutamyltransferase (P = .046), and a positive increase in HDL-C (P = .044). In men, additionally, favorable changes were observed in total cholesterol (P = .004), glucose (P = .015), albumin (P = .028), aspartate aminotransferase (P = .012), gamma-glutamyltransferase (P = .013), and HDL-C (P = .009; in this group, LDL-C increased IP = .007]). Changes in other parameters were not significant, for both women and men. Thus, the regular intake of bilberries can be important to reduce CVDs risk, by decreasing LDL-C/TG and increasing HDL-C. (C) 2016 Elsevier Inc. All rights reserved.
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