4.8 Article

Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression

Pierre-Olivier Esteve et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity

Olga V. Lukashevich et al.

BMC BIOCHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B

Gregoire Rondelet et al.

JOURNAL OF STRUCTURAL BIOLOGY (2016)

Article Multidisciplinary Sciences

Structural basis for activity regulation of MLL family methyltransferases

Yanjing Li et al.

NATURE (2016)

Article Multidisciplinary Sciences

DNA methylation on N6-adenine in mammalian embryonic stem cellse

Tao P. Wu et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

A two-state activation mechanism controls the histone methyltransferase Suv39h1

Manuel M. Mueller et al.

NATURE CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

The SNF2 family ATPase LSH promotes cell-autonomous de novo DNA methylation in somatic cells

Ausma Termanis et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Multidisciplinary Sciences

Human DNMT1 transition state structure

Quan Du et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells

Christopher E. Duymich et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition

Jian Fang et al.

NATURE COMMUNICATIONS (2016)

Review Biochemistry & Molecular Biology

PIWI-Interacting RNA: Its Biogenesis and Functions

Yuka W. Iwasaki et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)

Article Biochemistry & Molecular Biology

DNA Methylation on N6-Adenine in C-elegans

Eric Lieberman Greer et al.

Article Biochemistry & Molecular Biology

N6-Methyladenine DNA Modification in Drosophila

Guoqiang Zhang et al.

Article Biochemistry & Molecular Biology

Crystal Structure of Human DNA Methyltransferase 1

Zhi-Min Zhang et al.

JOURNAL OF MOLECULAR BIOLOGY (2015)

Article Multidisciplinary Sciences

Disruption of DNA-methylation-dependent long gene repression in Rett syndrome

Harrison W. Gabel et al.

NATURE (2015)

Article Multidisciplinary Sciences

Human body epigenome maps reveal noncanonical DNA methylation variation

Matthew D. Schultz et al.

NATURE (2015)

Review Genetics & Heredity

RNA-mediated epigenetic regulation of gene expression

Daniel Holoch et al.

NATURE REVIEWS GENETICS (2015)

Review Cell Biology

DNA N6-methyladenine: a new epigenetic mark in eukaryotes?

Guan-Zheng Luo et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation

Guoqiang Zhang et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Multidisciplinary Sciences

MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome

Lin Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Genetics & Heredity

Genetic alterations of DNA methylation machinery in human diseases

Tewfik Hamidi et al.

EPIGENOMICS (2015)

Article Multidisciplinary Sciences

Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation

Jingdong Cheng et al.

NATURE COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

The UHRF1 Protein Stimulates the Activity and Specificity of the Maintenance DNA Methyltransferase DNMT1 by an Allosteric Mechanism

Pavel Bashtrykov et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Cooperative DNA Binding and Protein/DNA Fiber Formation Increases the Activity of the Dnmt3a DNA Methyltransferase

Max Emperle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Review Genetics & Heredity

RNA-directed DNA methylation: an epigenetic pathway of increasing complexity

Marjori A. Matzke et al.

NATURE REVIEWS GENETICS (2014)

Review Biochemistry & Molecular Biology

Structure and function of the nucleosome-binding PWWP domain

Su Qin et al.

TRENDS IN BIOCHEMICAL SCIENCES (2014)

Review Biochemistry & Molecular Biology

New concepts in DNA methylation

Albert Jeltsch et al.

TRENDS IN BIOCHEMICAL SCIENCES (2014)

Article Biochemistry & Molecular Biology

Dynamic DNA methylation across diverse human cell lines and tissues

Katherine E. Varley et al.

GENOME RESEARCH (2013)

Article Multidisciplinary Sciences

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication

Atsuya Nishiyama et al.

NATURE (2013)

Article Multidisciplinary Sciences

DNMT1-interacting RNAs block gene-specific DNA methylation

Annalisa Di Ruscio et al.

NATURE (2013)

Review Biochemistry & Molecular Biology

DNA methylation dynamics in health and disease

Yehudit Bergman et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

Article Multidisciplinary Sciences

Global Epigenomic Reconfiguration During Mammalian Brain Development

Ryan Lister et al.

SCIENCE (2013)

Review Multidisciplinary Sciences

Epigenetic Reprogramming in Cancer

Mario L. Suva et al.

SCIENCE (2013)

Article Genetics & Heredity

Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain

Rick van Nuland et al.

EPIGENETICS & CHROMATIN (2013)

Review Biochemistry & Molecular Biology

Genome Regulation by Long Noncoding RNAs

John L. Rinn et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)

Article Biochemistry & Molecular Biology

Specificity of Dnmt1 for Methylation of Hemimethylated CpG Sites Resides in Its Catalytic Domain

Pavel Bashtrykov et al.

CHEMISTRY & BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase

Pavel Bashtrykov et al.

FEBS LETTERS (2012)

Review Genetics & Heredity

Functions of DNA methylation: islands, start sites, gene bodies and beyond

Peter A. Jones

NATURE REVIEWS GENETICS (2012)

Article Biochemistry & Molecular Biology

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

Scott B. Rothbart et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Function and disruption of DNA Methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation

Arumugam Rajavelu et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biochemistry & Molecular Biology

RNA modulation of the human DNA methyltransferase 3A

Celeste Holz-Schietinger et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Multidisciplinary Sciences

Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation

Jikui Song et al.

SCIENCE (2012)

Article Genetics & Heredity

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases

Julia Arand et al.

PLOS GENETICS (2012)

Article Biochemistry & Molecular Biology

Characterization of DNA-binding activity in the N-terminal domain of the DNA methyltransferase Dnmt3a

Isao Suetake et al.

BIOCHEMICAL JOURNAL (2011)

Article Biology

PKC isoforms interact with and phosphorylate DNMT1

Genevieve Lavoie et al.

BMC BIOLOGY (2011)

Article Biochemistry & Molecular Biology

The Multifaceted Roles of USP7: New Therapeutic Opportunities

Benjamin Nicholson et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2011)

Review Biochemistry & Molecular Biology

Structure and Function of Mammalian DNA Methyltransferases

Renata Zofia Jurkowska et al.

CHEMBIOCHEM (2011)

Article Biochemistry & Molecular Biology

Approaches to Enzyme and Substrate Design of the Murine Dnmt3a DNA Methyltransferase

Renata Z. Jurkowska et al.

CHEMBIOCHEM (2011)

Article Biochemistry & Molecular Biology

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

Arunkumar Dhayalan et al.

HUMAN MOLECULAR GENETICS (2011)

Article Biochemistry & Molecular Biology

Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein

Nataliya Nady et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

The Replication Focus Targeting Sequence (RFTS) Domain Is a DNA-competitive Inhibitor of Dnmt1

Farisa Syeda et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Oligomerization and Binding of the Dnmt3a DNA Methyltransferase to Parallel DNA Molecules HETEROCHROMATIC LOCALIZATION AND ROLE OF Dnmt3L

Renata Z. Jurkowska et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Usp7 and Uhrf1 Control Ubiquitination and Stability of the Maintenance DNA Methyltransferase Dnmt1

Weihua Qin et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Distinct Roles of DMAP1 in Mouse Development

K. Naga Mohan et al.

MOLECULAR AND CELLULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities

Lirong Peng et al.

MOLECULAR AND CELLULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression

Eerappa Rajakumara et al.

MOLECULAR CELL (2011)

Article Multidisciplinary Sciences

Mapping and analysis of chromatin state dynamics in nine human cell types

Jason Ernst et al.

NATURE (2011)

Article Genetics & Heredity

Dynamic CpG island methylation landscape in oocytes and preimplantation embryos

Sebastien A. Smallwood et al.

NATURE GENETICS (2011)

Article Biochemistry & Molecular Biology

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

Pierre-Olivier Esteve et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Nucleosomes protect DNA from DNA methylation in vivo and in vitro

Max Felle et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Biochemistry & Molecular Biology

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

Max Felle et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Multidisciplinary Sciences

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

Kohei Takeshita et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Oncology

A decade of exploring the cancer epigenome - biological and translational implications

Stephen B. Baylin et al.

NATURE REVIEWS CANCER (2011)

Article Biochemistry & Molecular Biology

Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion

Matthew M. Purdy et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)

Article Biochemistry & Molecular Biology

The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1δ/ε

Yasunori Sugiyama et al.

BIOCHEMICAL JOURNAL (2010)

Article Biochemistry & Molecular Biology

The Inherent Processivity of the Human de Novo Methyltransferase 3A (DNMT3A) Is Enhanced by DNMT3L

Celeste Holz-Schietinger et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation

Arunkumar Dhayalan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Multidisciplinary Sciences

Relationship between nucleosome positioning and DNA methylation

Ramakrishna K. Chodavarapu et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

Yingying Zhang et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Biochemistry & Molecular Biology

DNMT1 Stability Is Regulated by Proteins Coordinating Deubiquitination and Acetylation-Driven Ubiquitination

Zhanwen Du et al.

SCIENCE SIGNALING (2010)

Review Genetics & Heredity

Molecular coupling of DNA methylation and histone methylation

Hideharu Hashimoto et al.

EPIGENOMICS (2010)

Article Biochemistry & Molecular Biology

Selective Anchoring of DNA Methyltransferases 3A and 3B to Nucleosomes Containing Methylated DNA

Shinwu Jeong et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

Human DNA methylomes at base resolution show widespread epigenomic differences

Ryan Lister et al.

NATURE (2009)

Article Biotechnology & Applied Microbiology

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

Madeleine P. Ball et al.

NATURE BIOTECHNOLOGY (2009)

Article Genetics & Heredity

Differential chromatin marking of introns and expressed exons by H3K36me3

Paulina Kolasinska-Zwierz et al.

NATURE GENETICS (2009)

Review Genetics & Heredity

OPINION Rethinking how DNA methylation patterns are maintained

Peter A. Jones et al.

NATURE REVIEWS GENETICS (2009)

Article Multidisciplinary Sciences

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

Pierre-Olivier Esteve et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

Chunaram Choudhary et al.

SCIENCE (2009)

Article Biochemistry & Molecular Biology

CXXC domain of human DNMT1 is essential for enzymatic activity

Mihika Pradhan et al.

BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Mouse Dnmt3a Preferentially Methylates Linker DNA and Is Inhibited by Histone H1

Hideyuki Takeshima et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Multidisciplinary Sciences

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

Hideharu Hashimoto et al.

NATURE (2008)

Article Multidisciplinary Sciences

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

George V. Avvakumov et al.

NATURE (2008)

Article Multidisciplinary Sciences

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Alexander Meissner et al.

NATURE (2008)

Review Genetics & Heredity

DNA methylation landscapes: provocative insights from epigenomics

Miho M. Suzuki et al.

NATURE REVIEWS GENETICS (2008)

Editorial Material Biochemistry & Molecular Biology

Reading and writing DNA methylation

Albert Jeltsch

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L

Renata Z. Jurkowska et al.

NUCLEIC ACIDS RESEARCH (2008)

Review Biochemistry & Molecular Biology

Mammalian DNA methyltransferases: A structural perspective

Xiaodong Cheng et al.

STRUCTURE (2008)

Article Biochemistry & Molecular Biology

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation

John W. Edmunds et al.

EMBO JOURNAL (2008)

Article Biochemistry & Molecular Biology

LSH cooperates with DNA Methyltransferases to repress transcription

Kevin Myant et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Synergistic function of DNA Methyltransferases dnmt3a and dnrnt3b in the methylation of Oct4 and Nanog

Jing-Yu Li et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism

Erica Larschan et al.

MOLECULAR CELL (2007)

Article Multidisciplinary Sciences

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

Magnolia Bostick et al.

SCIENCE (2007)

Article Multidisciplinary Sciences

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

Steen K. T. Ooi et al.

NATURE (2007)

Article Multidisciplinary Sciences

Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX

Anthony Argentaro et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

A chromatin landmark and transcription initiation at most promoters in human cells

Matthew G. Guenther et al.

Article Biochemistry & Molecular Biology

Phosphorylation of serine-515 activates the mammalian maintenance methyltransferase Dnmt1

Rachna Goyal et al.

EPIGENETICS (2007)

Article Biochemistry & Molecular Biology

High-resolution profiling of histone methylations in the human genome

Artern Barski et al.

Article Biochemistry & Molecular Biology

Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression

Sung-Hak Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Multidisciplinary Sciences

Gene body-specific methylation on the active X chromosome

Asaf Hellman et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Profile of histone lysine methylation across transcribed mammalian chromatin

Christopher R. Vakoc et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Genetics & Heredity

DNA methylation profiling of human chromosomes 6, 20 and 22

Florian Eckhardt et al.

NATURE GENETICS (2006)

Article Multidisciplinary Sciences

Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival

Gerda Egger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L

Michael S. Kareta et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

Sung Chan Kim et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b

M Suzuki et al.

ONCOGENE (2006)

Article Biochemistry & Molecular Biology

Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase

H Gowher et al.

JOURNAL OF MOLECULAR BIOLOGY (2006)

Article Multidisciplinary Sciences

The Polycomb group protein EZH2 directly controls DNA methylation

E Viré et al.

NATURE (2006)

Review Biochemistry & Molecular Biology

Genomic DNA methylation: the mark and its mediators

RJ Klose et al.

TRENDS IN BIOCHEMICAL SCIENCES (2006)

Article Biochemistry & Molecular Biology

Lsh is involved in de novo methylation of DNA

HM Zhu et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase

R Goyal et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

Lsh, a guardian of heterochromatin at repeat elements

K Muegge

BIOCHEMISTRY AND CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family

ZX Chen et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases

H Gowher et al.

BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

DNA cytosine C5 methyltransferase Dnmt1:: Catalysis-dependent release of allosteric inhibition

ZM Svedruzic et al.

BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Profound flanking sequence preference of Dnmt3a and Dnmt3b mammalian DNA methyltransferases shape the human epigenome

V Handa et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L

H Gowher et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Myc represses transcription through recruitment of DNA methyltransferase corepressor

C Brenner et al.

EMBO JOURNAL (2005)

Article Biochemistry & Molecular Biology

Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase

G Vilkaitis et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Biochemistry and biology of mammalian DNA methyltransferases

A Hermann et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2004)

Article Biochemistry & Molecular Biology

Replication-independent chromatin loading of Dnmt1 during G2 and M phases

HP Easwaran et al.

EMBO REPORTS (2004)

Article Biochemistry & Molecular Biology

The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites

A Hermann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction

I Suetake et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Chromatin targeting of de novo DNA methyltransferases by the PWWP domain

YZ Ge et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system

TM Geiman et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Biochemistry & Molecular Biology

Interactions within the mammalian DNA methyltransferase family

JB Margot et al.

BMC MOLECULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

F Fuks et al.

NUCLEIC ACIDS RESEARCH (2003)

Article Biochemistry & Molecular Biology

A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase

J Flynn et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1

H Kimura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

The Methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

F Fuks et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

F Chédin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

In vivo stabilization of the Dnmt1 (cytosine-5)-methyltransferase protein

F Ding et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA

M Fatemi et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases

H Gowher et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Dnmt3L and the establishment of maternal genomic imprints

D Bourc'his et al.

SCIENCE (2001)

Review Biochemistry & Molecular Biology

AdoMet-dependent methylation, DNA methyltransferases and base flipping

XD Cheng et al.

NUCLEIC ACIDS RESEARCH (2001)

Article Biochemistry & Molecular Biology

Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases

A Aoki et al.

NUCLEIC ACIDS RESEARCH (2001)

Article Genetics & Heredity

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

MR Rountree et al.

NATURE GENETICS (2000)

Article Multidisciplinary Sciences

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a

BH Ramsahoye et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)