Related references
Note: Only part of the references are listed.DNMT3A R882 Mutation with FLT3-ITD Positivity Is an Extremely Poor Prognostic Factor in Patients with Normal-Karyotype Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation
Jae-Sook Ahn et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2016)
Co-occurrence of MYC amplification and TP53 mutations in human cancer
Peter Ulz et al.
NATURE GENETICS (2016)
Shared and unique mutational gene co-occurrences in cancers
Junqi Liu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease
Rebecca M. Hill et al.
CANCER CELL (2015)
Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing
Reika Iwakawa et al.
CARCINOGENESIS (2015)
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
Jiajun Zhu et al.
NATURE (2015)
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors
Jeanette E. Eckel-Passow et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Identifying core gene modules in glioblastoma based on multilayer factor-mediated dysfunctional regulatory networks through integrating multi-dimensional genomic data
Yanyan Ping et al.
NUCLEIC ACIDS RESEARCH (2015)
High burden and pervasive positive selection of somatic mutations in normal human skin
Inigo Martincorena et al.
SCIENCE (2015)
Diagnosing phenotypes of single-sample individuals by edge biomarkers
Wanwei Zhang et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2015)
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
Terrence N. Wong et al.
NATURE (2015)
In Vitro Maturation in Women with vs. without Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis
Charalampos Siristatidis et al.
PLOS ONE (2015)
Inferring the paths of somatic evolution in cancer
Navodit Misra et al.
BIOINFORMATICS (2014)
Discovery of co-occurring driver pathways in cancer
Junhua Zhang et al.
BMC BIOINFORMATICS (2014)
Most Human Non-GCIMP Glioblastoma Subtypes Evolve from a Common Proneural-like Precursor Glioma
Tatsuya Ozawa et al.
CANCER CELL (2014)
Integration of Genomic Data Enables Selective Discovery of Breast Cancer Drivers
Felix Sanchez-Garcia et al.
CELL (2014)
Clinical features of De Novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations
Sanam Loghavi et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2014)
IndividualizedPath: identifying genetic alterations contributing to the dysfunctional pathways in glioblastoma individuals
Yanyan Ping et al.
MOLECULAR BIOSYSTEMS (2014)
Discovery and saturation analysis of cancer genes across 21 tumour types
Michael S. Lawrence et al.
NATURE (2014)
An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer
Michael L. Gatza et al.
NATURE GENETICS (2014)
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis
Jamie M. J. Weaver et al.
NATURE GENETICS (2014)
GBM's multifaceted landscape: highlighting regional and microenvironmental heterogeneity
Alenoush Vartanian et al.
NEURO-ONCOLOGY (2014)
Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo
I. A. Elsum et al.
ONCOGENE (2014)
Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations
R. A. Gatenby et al.
NATURE COMMUNICATIONS (2014)
Pten Loss Induces Autocrine FGF Signaling to Promote Skin Tumorigenesis
Kristina Hertzler-Schaefer et al.
CELL REPORTS (2014)
tRNA Modifying Enzymes, NSUN2 and METTL1, Determine Sensitivity to 5-Fluorouracil in HeLa Cells
Mayumi Okamoto et al.
PLOS GENETICS (2014)
Network analysis of genomic alteration profiles reveals co-altered functional modules and driver genes for glioblastoma
Yunyan Gu et al.
MOLECULAR BIOSYSTEMS (2013)
The causes and consequences of genetic heterogeneity in cancer evolution
Rebecca A. Burrell et al.
NATURE (2013)
Mutational landscape and significance across 12 major cancer types
Cyriac Kandoth et al.
NATURE (2013)
The Cancer Genome Atlas Pan-Cancer analysis project
John N. Weinstein et al.
NATURE GENETICS (2013)
Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: A case study of glioblastoma
Yun Xiao et al.
NEURO-ONCOLOGY (2013)
Simultaneous Identification of Multiple Driver Pathways in Cancer
Mark D. M. Leiserson et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Life history trade-offs in cancer evolution
C. Athena Aktipis et al.
NATURE REVIEWS CANCER (2013)
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
Dominik Sturm et al.
CANCER CELL (2012)
Wild-Type Tumor Repressor Protein 53 (TRP53) Promotes Ovarian Cancer Cell Survival
Lisa K. Mullany et al.
ENDOCRINOLOGY (2012)
Mutual exclusivity analysis identifies oncogenic network modules
Giovanni Ciriello et al.
GENOME RESEARCH (2012)
The DNA damage response and cancer therapy
Christopher J. Lord et al.
NATURE (2012)
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
Christina Curtis et al.
NATURE (2012)
Evolution of the cancer genome
Lucy R. Yates et al.
NATURE REVIEWS GENETICS (2012)
Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF
F. Xing et al.
ONCOGENE (2012)
Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers
Luonan Chen et al.
SCIENTIFIC REPORTS (2012)
Abundant Pleiotropy in Human Complex Diseases and Traits
Shanya Sivakumaran et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
CDCOCA: A statistical method to define complexity dependence of co-occuring chromosomal aberrations
Nitin Kumar et al.
BMC MEDICAL GENOMICS (2011)
Cooperativity within and among Pten, p53, and Rb Pathways Induces High-Grade Astrocytoma in Adult Brain
Lionel M. L. Chow et al.
CANCER CELL (2011)
Finding co-mutated genes and candidate cancer genes in cancer genomes by stratified false discovery rate control
Jing Wang et al.
MOLECULAR BIOSYSTEMS (2011)
Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms
Pixu Liu et al.
NATURE MEDICINE (2011)
Predicting the functional impact of protein mutations: application to cancer genomics
Boris Reva et al.
NUCLEIC ACIDS RESEARCH (2011)
GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
Craig H. Mermel et al.
GENOME BIOLOGY (2011)
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Houtan Noushmehr et al.
CANCER CELL (2010)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak et al.
CANCER CELL (2010)
Systematic Interpretation of Comutated Genes in Large-Scale Cancer Mutation Profiles
Yunyan Gu et al.
MOLECULAR CANCER THERAPEUTICS (2010)
A Network of Cancer Genes with Co-Occurring and Anti-Co-Occurring Mutations
Qinghua Cui
PLOS ONE (2010)
A mathematical framework to determine the temporal sequence of somatic genetic events in cancer
Camille Stephan-Otto Attolini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Accumulation of driver and passenger mutations during tumor progression
Ivana Bozic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Identification of Networks of Co-Occurring, Tumor-Related DNA Copy Number Changes Using a Genome-Wide Scoring Approach
Christiaan Klijn et al.
PLOS COMPUTATIONAL BIOLOGY (2010)
Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of EIF3H
Alan M. Pittman et al.
PLOS GENETICS (2010)
A Network Model of a Cooperative Genetic Landscape in Brain Tumors
Markus Bredel et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution
Jamie T. Bridgham et al.
NATURE (2009)
Combinatorial patterns of somatic gene mutations in cancer
Chen-Hsiang Yeang et al.
FASEB JOURNAL (2008)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
Malignant gliomas in adults
Patrick Y. Wen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras
Katrina Podsypanina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Modeling synthetic lethality
Nolwenn Le Meur et al.
GENOME BIOLOGY (2008)
Opinion - Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
John Stingl et al.
NATURE REVIEWS CANCER (2007)
A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma
Robert B. Jenkins et al.
CANCER RESEARCH (2006)
Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways
David M. Levine et al.
GENOME BIOLOGY (2006)
High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma
K Oda et al.
CANCER RESEARCH (2005)
Applied bioinformatics for the identification of regulatory elements
WW Wasserman et al.
NATURE REVIEWS GENETICS (2004)
Astrocyte-specific expression of CDK4 is not sufficient for tumor formation, but cooperates with p53 heterozygosity to provide a growth advantage for astrocytes in vivo
ZY Huang et al.
ONCOGENE (2002)