4.5 Article

Analysis of stability and Hopf bifurcation for HIV-1 dynamics with PI and three intracellular delays

Journal

NONLINEAR ANALYSIS-REAL WORLD APPLICATIONS
Volume 27, Issue -, Pages 55-69

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.nonrwa.2015.07.014

Keywords

Bifurcation; Delays; Global stability; HIV-1; Lyapunov functionals

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Mathematical model for the effects of protease inhibitor on the dynamics of HIV-1 infection model with three delays is proposed and analyzed. Some analytical results on the global stability of viral free steady state and infected steady state are obtained. The stability/instability of the positive steady state and associated Hopf bifurcation are investigated by analyzing the characteristic equations. (C) 2015 Elsevier Ltd. All rights reserved.

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