Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 357, Issue 14-15, Pages 3109-3114Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201500391
Keywords
biimidazo[1,2-a]pyridines; C-C bond formation; copper catalysis; homocoupling; imidazo[1,2-a]pyridines
Categories
Funding
- National Natural Science Foundation of China [21302023]
- Department of Education of Guangdong, China [2013KJCX0111, 2014KTSCX120]
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A facile and efficient copper(I)-catalyzed intermolecular direct C-H homocoupling of imidazo[1,2-a]pyridines with excellent C-3 regioselectivity in dimethyl sulfoxide (DMSO) has been developed. This transformation provides a straightforward and operationally simple route for the preparation of biimidazo[1,2-a]pyridines which are an important structural motif in natural products and pharmaceuticals.
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