Journal
CHEMISTRY & BIODIVERSITY
Volume 12, Issue 10, Pages 1481-1515Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201400227
Keywords
Cytotoxic activity; Eupatorium; Flavonoids; Insecticidal activity; Pharmacological activity; Terpenoids
Funding
- National Natural Science Foundation of China [81302664, 81072551, 81241101]
- Natural Science Foundation of Hebei Province [H2013206103]
- Youth Science Foundation of Hebei Ministry of Education [2011172]
- Syngenta Ltd.
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Eupatorium (family: Compositae), which comprises nearly 1200 species, is distributed throughout tropical America, Europe, Africa, and Asia. Up to now, the reported constituents from the genus Eupatorium involve flavonoids, terpenoids, pyrrolizidine alkaloids, phenylpropanoids, quinonoids, essential oils, and some others, altogether more than 300 compounds. Studies have shown that Eupatorium and its active principles possess a wide range of pharmacological activities, such as cytotoxic, antifungal, insecticidal, antibacterial, anti-inflammatory, and antinociceptive activities. Currently, effective monomeric compounds or active parts have been screened for pharmacological activities from Eupatorium in vivo and in vitro. Increasing amount of data supports application and exploitation for new drug development.
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